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While being a tricky disease, osteoarthritis affects people all of a sudden. As a result, such unpleasant symptoms as the loss of flexibility, bone spur, or joint pain appear for no apparent reason. What makes the situation even more unpleasant is that osteoarthritis is a chronic health condition. Therefore, it cannot be completely cured as of now.

Fortunately, there exist several brands that produce efficient medications to temporarily reduce the symptoms of osteoarthritis. Namely, Durolane, Orthovisc, Hymovis, Hyalgan, and Synvisc are well-known trademarks that manufacture injectable solutions for joint pain relief. Despite being similar in action, they all have their own peculiarities.

In the information below, you will be able to check out a detailed overview of the Synvisc brand. Let us go through its composition, usage indications, contraindications, treatment protocol, after-treatment recovery rules, side effects, expected results, and key benefits.

About the Synvisc Brand

As its website suggests, the Synvisc brand produces medications that have the power to quickly relieve a patient’s knee joint pain by means of cushioning and lubricating it. It is manufactured by a Sanofi company (France).

Synvisc stands side-by-side with the following trademarks of Sanofi:

  • Adlyxin;
  • Apidra;
  • Dupixent;
  • Ranexa;
  • Allegra;
  • And many other solutions.

In other words, the Sanofi company manufactures different kinds of products, starting from diabetes mellitus medications and ending with products to treat allergies.

The main product of the Synvisc brand is Synvisc-One. It is a safe, efficient, and long-lasting injectable solution that reduces knee pain in patients with osteoarthritis.

Synvisc-One is a prescription medication that is oftentimes covered by different insurance plans.


Interestingly enough, the main active ingredients of Synvisc-One are hylan-polymers. These are the substances that might be found in chicken combs. As well, other essential elements of the product’s composition are sodium chlorides. Once being injected into an intended joint of a patient, the combination of these ingredients efficiently replaces its synovial fluid.

Please note: There exists a great number of hyaluronan products that are also used to treat joint pain in patients with osteoarthritis.

Indication for a Synvisc Injection

The primary aim of the Synvisc injection is to provide a patient suffering from osteoarthritis with knee joint pain relief. When being more precise, however, the product is intended to reduce the feeling of discomfort in patients who failed to respond adequately to other medical methods, such as:

  • Physical therapy;
  • The intake of simple analgesics;
  • And other non-pharmacological methods to take care of joint pain.


Not each and every patient with osteoarthritis is a good candidate for a Synvisc-One injection. Namely, the product should not be administered under one of the following circumstances:

  • An allergic reaction to any component of the Synvisc-One composition (including the known hypersensitivity to birds, feathers, and egg products);
  • A severe health complication (like diabetes mellitus, untreated epilepsy, or autoimmune disorder);
  • An ongoing infection of the treated joint or around it.

As well, Synvisc-One is not recommended to be used if a patient is:

  • Under the age of 21;
  • Pregnant;
  • Breastfeeding.

Synvisc-One is indicated to treat pain in knee joints. Therefore, it is contraindicated to take care of osteoarthritis-related discomfort in the hips, ankles, elbows, shoulders, fingers, or toes.

Treatment Protocol

First and foremost, Synvisc-One should be administered exclusively by healthcare professionals. The product is not suitable for home-usage.

Synvisc-One should be injected directly into the treated joint. As the product’s name suggests, a patient needs only one administration of the product in most cases.

It is the task of certified healthcare professionals to provide patients with medical advice, diagnosis or treatment recommendations.

After-Treatment Recovery Rules

The injection of Synvisc-One requires little to no downtime. Under normal circumstances, patients are expected to return to their usual lifestyles shortly after the procedure.

Still, there exist several after-treatment recovery rules that aim to minimize the appearance of any complications after the procedure and maximize its effectiveness.

For the first 48 hours after the procedure, a patient should:

  • Evade being overactive;
  • Avoid strenuous and weight-bearing activities;
  • Apply a pack of ice to the injection site in case of experiencing any feeling of discomfort.

Possible Side Effects

The most widely-spread side effects that occur in patients after a Synvisc-One injection include:

  • The feeling of pain or discomfort around the injection site;
  • The fluid buildup around the area of the treatment;
  • Joint stiffness or swelling.

Some patients also claim to experience symptoms of headache after the administration of Synvisc-One.

In most cases, these side effects have mild to middle intensity. Moreover, they tend to disappear on their own within several days after the treatment.

Still, a patient should contact a medical professional as soon as possible in case of noticing any complications after the injection of Synvisc-One.

Expected Results

It is a false assumption that the effect of Synvisc will be noticeable immediately. In most cases, patients with osteoarthritis mention starting to experience significant pain relief during the fourth week after the procedure.

On average, the result of the Synvisc treatment lasts up to six months. However, it strongly depends on such individual characteristics of each patient as age, health condition, and lifestyle.

The injection of Synvisc-One might be repeated once its efficiency is over. However, a patient should consult with a health care practitioner beforehand.

Key Benefits

Synvisc-One is one of the most advantageous solutions in the sphere of treatments for osteoarthritis. Among the key benefits of the product are:

  • Convenience. Only one injection of Synvisc-One is needed to achieve the desired result;
  • Safety. The product causes little to no side effects in most cases;
  • Durability. A single injection of Synvisc-One lasts up to six months;
  • Efficiency. The vast majority of patients who used the product claim to acquire a substantially reduced pain in the target knee joint in four weeks after the procedure.

Thus, the administration of Synvisc-One is a convenient, safe, long-lasting, and efficient method of treating osteoarthritis-related joint pain in the knee.

How much do Synvisc injections cost?

The price of Synvisc on Fillercloud varies depending on the quantity and type of Synvisc used. Fillerlcoud offers bulk pricing for orders of 6 packs or more.

Synvisc price

Product Price
Synvisc One (1x6ml) $339
Synvisc (3x2ml) $329

Buy Synvisc Online at Fillercloud

It might be challenging to find a reliable online supplier of original medical and cosmetic injectables. Namely, you might switch between branded and unbranded site tabs, read numerous reviews, compare prices on them, and still find it difficult to make a decision.

Or you might simply rely on Fillercloud, which is an online pharmacy that offers the following benefits to its clients:

  • A wide range of authentic products from well-known brands;
  • Affordable wholesale prices;
  • Quick delivery all around the world.

Moreover, Fillercloud belongs to online pharmacies that offer a professional customer support team that is eager to help you out and answer all your questions.

Only licensed health care providers are eligible to buy prescription medications and cosmetic injectables on a Fillercloud website.

So, visit a website of a Fillercloud pharmacy and place your order at any time. We are looking forward to cooperating with you!

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