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According to the recent surveys, neuromodulator injections are among the most popular procedures in 2025. The main reason is that by using the same active ingredient, specialists may fulfill both cosmetic and medical goals, which is definitely beneficial for patients. Today, we would like to compare two injectable treatments that are often compared in the aesthetic medicine sphere – Jeuveau and Xeomin. Due to the same components, they may be replaced with one another; however, there are some subtle differences that should be noted.
If you’re a board-certified specialist looking to purchase high-quality Xeomin or Jeuveau, we recommend checking all the available products on our website. There are plenty of options to pick from, so don’t hesitate to get in touch if you need products for your clinic!
Before deciding which brand is best for your patients, let’s discuss some essential considerations about them. Below, we will list the main features of Xeomin and Jeuveau, so you can see them for yourself and decide which ones best match the customers’ needs. Each patient is unique, which is why there’s no one correct answer when it comes to picking the brand for a cosmetic procedure.
| Feature | Xeomin | Jeuveau |
|---|---|---|
| Type | Botulinum toxin type A (incobotulinumtoxinA) | Botulinum toxin type A (prabotulinumtoxinA-xvfs) |
| Manufactured by | Merz Pharmaceuticals | Evolus |
| FDA Approval | 2010 (for frown lines) | 2019 (for frown lines) |
| Formulation | Naked toxin – no complexing proteins | Complexing proteins present |
| Storage | No refrigeration required before reconstitution | Requires refrigeration before use |
| Primary Use | Medical and cosmetic | Primarily cosmetic |
| Onset of Results | 3–4 days | 2–3 days |
| Duration of Results | 3–4 months | 3–4 months |
| Cost | Slightly higher per unit | Generally more affordable per unit |
| Best For | Patients seeking a purified product with minimal risk of antibody formation | Patients focused on aesthetics and cost-effectiveness |
Both products belong to the botulinum toxin treatment category, meaning they target nerve endings, blocking nerve signals and temporarily stopping facial muscle movement.
Xeomin contains purified form of botulinum toxin type A and is free from additional proteins, which significantly reduces the risk of developing antibody formation. The incobotulinumtoxinA ingredient distinguishes Xeomin from other neuromodulator injections available on the market.
On the other hand, Jeuveau has a newer botulinum toxin type A formulation and ingredient – prabotulinumtoxinA-xvfs. The new design is formulated as a vacuum-dried powder for injection.
Although there are differences, the mechanism of action is similar, which is why these brands can easily be substituted for one another.
When comparing these brands, the main differences when it comes to common uses are their tasks that are FDA-approved. Let’s take a closer look at the main points you should keep in mind:
Xeomin uses. When it comes to aesthetic uses, it’s suitable for severe frown lines, crow’s feet, glabellar lines, etc. Approved medical conditions include upper limb spasticity, chronic sialorrhea, cervical dystonia, blepharospasm, and others;
Jeuveau uses. This product is primarily chosen for aesthetic purposes, such as fine lines and wrinkles caused by active facial movements, including talking, smiling, frowning, etc.
When it comes to the onset of action, Jeuveau works faster than Xeomin because it uses smaller and more uniform proteins in its composition. Xeomin may need from a week to three weeks to demonstrate the results, while for Jeuveau, three days are enough to see the effect.
To achieve the desired effect, 20 to 40 units of the solution are sufficient. Everything depends on the severity of the problem, the size of the target area, and the patient’s age.
As for longevity, Xeomin typically lasts for three months, while Jeuveau lasts for five months and sometimes even longer for some patients. Everything depends on one’s unique characteristics.
Treatments must always be performed by experienced providers to achieve beneficial results. They set the price themselves, and it depends on numerous factors: the area of the clinic, the cost of the product from a supplier, a professional’s experience, and numerous others. The average price per unit ranges from $10 to $20, but this may vary. We recommend discussing this nuance beforehand to ensure a clear understanding of the pricing.
Unfortunately, there’s no correct answer when it comes to choosing between Jeuveau and Xeomin. Both products got their FDA approval in terms of fine lines battling, and the only difference is the intensity of the results, slight variations in terms of longevity, as well as the target areas. But one thing remains the same: in order to know which product to choose for your needs, you must talk to a medical professional, point out all the concerns and desired goals, and create a treatment plan according to your personal needs.
Both Jeuveau and Xeomin can be used for medical and aesthetic purposes. Regarding cosmetic goals, people who can benefit from the treatment are those who struggle with facial wrinkles that occur because of active facial movement (also known as dynamic lines). We are referring to severe glabellar lines, horizontal forehead lines, crow’s feet, and other wrinkles. Sometimes botulinum toxins are used with other cosmetic injectables to achieve a more youthful appearance and long-lasting results.
It’s essential for patients to be at least 18 years old (if we’re discussing the cosmetic use of botulinum toxins; however, a medical recommendation from a doctor allows for its use in younger patients). The treatment area must be healthy, without any damage or injuries. It is also vital to discuss all the limitations in the doctor’s office to ensure this type of procedure is safe for an individual and is able to fulfill their needs.
Note: We offer high-quality products on FillerCloud, so be sure to explore everything available and place your order to begin your journey with our company. We respect and appreciate every customer!
The right option should always be picked according to the patient’s needs and goals. Both Jeuveau and Xeomin are suitable for aesthetic and medical purposes, and the treatment protocol should be discussed with a medical professional to determine the optimal formula for the treatment.
The main difference between these two products with regard to the active ingredient is that Xeomin contains pure botulinum toxin type A and doesn’t contain additional proteins, while Jeuveau contains botulinum toxin with additional proteins. This is the main reason why they may differ in terms of the mechanism of action and durability.
Jeuveau and Xeomin are often compared to Botox, but they are definitely not the same. They all contain the same active component – botulinum toxin type A – but Xeomin is known as a purer form of Botox, while Jeuveau is a botulinum toxin injectable of a new generation with an improved formulation. The best choice here depends on individual factors, which is why consulting a professional is essential.
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