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Minimally invasive treatments are among the most popular in the aesthetic field today. They are preferred by people with tight schedules who don’t have time for hours-long procedures, as well as durable recovery; thus, they pick treatments such as dermal fillers, botulinum toxins, and skin boosters. The last category is exactly what we would like to discuss today.
Skin boosters are perfect for skin regeneration and rejuvenation. They improve the overall skin quality, including its tone, texture, and firmness. Two popular products specialists often use for skin booster aesthetic treatments are NCTF 135 HA and Profhilo. Furthermore, they are often mistaken for one another because of similar goals, but their characteristics differ significantly, so it’s essential to understand these differences to select the best products for patients’ unique needs. This article is dedicated to this discussion: how to distinguish Profhilo and NCTF 135 HA? What are their main differences? Which benefits should we always pay attention to? Read the article and find out all the answers yourself!
The variety of products for non-surgical skin rejuvenation on the market is truly impressive. Various items can address different issues, which is why it is important to tailor the treatment plan to one’s needs and conditions. So, let’s explain what skin boosters are.
“Skin boosters have revolutionized how we approach aging skin. They’re not about changing your face—they’re about making your skin the healthiest version of itself.” — Dr. Maria Castellano, Aesthetic Medicine Specialist
Unlike traditional dermal fillers, which are designed to restore volume and smooth fine lines and wrinkles, skin boosters focus on improving skin texture, tone, firmness, and overall health. It’s a perfect solution for patients with dry skin that needs deep hydration, enhances skin quality, and delivers significant results without tedious, time-consuming treatments. Understanding each product’s unique formulation helps specialists tailor the procedure to their needs and achieve desired results quickly.
The aesthetic field continues to advance, which is why so many products are released on the market nowadays to fulfill the needs of even the most fastidious customers. NCTF 135 HA and Profhilo are more traditional skin boosters that are used for comprehensive skin rejuvenation. They can target different skin concerns and provide noticeable effects that last a long time. In this section, we will compare the two products and explain how they differ.
The first and most basic thing we would like to highlight is the active ingredients and mechanism of action of both brands. Here are the essentials you should keep in mind:
Profhilo. Unlike traditional skin boosters, Profhilo contains one of the highest concentrations of ultra-pure hyaluronic acid on the market. That allows it to stimulate collagen production, deeply hydrate the skin, and restore the skin barrier that could have been damaged by various external factors: sun damage, health issues, environmental problems, etc.
NCTF 135 HA. As for the composition of this product, it is slightly different from Profhilo. This skin booster contains over 50 active ingredients: 5mg/ml of non-crosslinked hyaluronic acid (HA), combined with 12 vitamins, 24 amino acids, 6 coenzymes, 6 minerals, and other essential nutrients. This unique formulation allows specialists to provide advanced treatments that support collagen production, improve overall skin tone and texture, enhance skin firmness, and provide a more youthful-looking skin in general.
“I think of Profhilo as pure hydration therapy, while NCTF is more like a nutritional supplement for the skin. Both work beautifully, but the approach is different.” — Dr. James Lee, Cosmetic Physician
Although the formulations differ, their mechanisms of action are similar: the skin is deeply hydrated, and collagen synthesis is supported to maintain an even-toned complexion and a natural glow.
Patients increasingly want better skin, not a different face, focusing on smoother texture and improved hydration. That’s exactly why both NCTF 135 HA and Profhilo are perfect for skin repair and provide numerous benefits.
NCTF 135 HA. This injectable treatment is an excellent option to target aged skin, eliminate fine lines, as well as hydrate dry dermis. It is also suitable for treating delicate areas like the under-eyes, neck, and hands. In addition, the product helps improve overall skin tone, texture, and radiance, especially for dull or fatigued skin.
Profhilo. This product focuses more on skin hydration, meaning Profhilo is particularly powerful for crepey skin, sagging, and dull, dehydrated skin. It can be safely used for any area of the body, including the face, neck, chest, hands, arms, and decolletage.
To determine whether these products are suitable for your needs and select the best skin booster, it is highly recommended to discuss this with a specialist during the pre-treatment consultation. A thorough consultation with licensed medical professionals can ensure patient suitability and safety.
Minimally invasive treatments have gained popularity due to their effectiveness and minimal downtime.
NCTF 135 HA is predominantly an epidermis and dermis injection that should be delivered into the target areas. It is often used in mesotherapy to deliver the solution via multiple small infusions. NCTF 135 HA requires three sessions spaced 15 days apart, with maintenance every six months.
Profhilo employs the BAP technique, which involves injecting at specific points in the treatment area for quicker sessions and recovery. Precise injection is the guarantee of faster and more prominent results. Profhilo often requires only one or two treatments, making it a more time-efficient option for many patients, considering maintenance treatments are only required every 6 months.
“My patients love Profhilo’s efficiency—two sessions and they’re done. But for those who want that extra nutritional boost, NCTF’s comprehensive formula is unmatched.” — Dr. Sophie Bennett, Dermatology Consultant
Both NCTF 135 HA and Profhilo offer long-lasting effects by stimulating collagen production. The effect typically becomes noticeable immediately after the session and improves over time. To maintain optimal results, specialists recommend scheduling maintenance procedures every 4 to 6 months (frequency varies based on individual conditions; discuss this with a medical professional during the consultation).
| Feature | NCTF 135 HA | Profhilo |
|---|---|---|
| Main Ingredient | 5mg/ml non-crosslinked HA + 50+ active ingredients (vitamins, amino acids, minerals) | Ultra-pure hyaluronic acid (one of highest concentrations available) |
| Primary Focus | Comprehensive skin nutrition and rejuvenation | Deep hydration and bio-remodeling |
| Best For | Aged skin, fine lines, dull/fatigued skin, delicate areas | Crepey skin, sagging, severe dehydration |
| Treatment Protocol | 3 sessions, 15 days apart | 1-2 sessions (BAP technique) |
| Injection Method | Mesotherapy (multiple small infusions) | BAP technique (specific injection points) |
| Maintenance | Every 6 months | Every 6 months |
| Treatment Areas | Face, under-eyes, neck, hands | Face, neck, chest, hands, arms, decolletage |
| Time Commitment | Higher (3 sessions required) | Lower (1-2 sessions) |
One of the benefits of Profhilo and NCTF 135 HA is that they can be easily combined with other aesthetic treatments to enhance results and address even the most stubborn skin concerns. Here are some of the most common combinations that are loved and used in the aesthetic industry:
Skin boosters + dermal fillers. This option is perfect for individuals with dull skin and prominent aging signs: nasolabial folds, marionette lines, smile lines, and others. While skin boosters hydrate the dermis, making it fresher and generally healthier, dermal fillers fill in creases and smooth out the facial surface to achieve an even complexion.
“I always start with skin boosters to create a healthy foundation, then use fillers strategically where needed. The skin quality improvement makes filler results look more natural and last longer.” — Dr. Carlos Mendez, Aesthetic Injector
Skin boosters + botulinum toxins. Dynamic lines are the most common wrinkles known to us. They occur when we move our face and can leave marks when the movement is repetitive (so, when we smile, frown, etc.). The combination of toxins and boosters prevents these marks and leaves skin smooth, glowing, and hydrated.
Skin boosters + laser treatments. Sometimes, skin may seem rough and uneven, and we may notice dark spots, post-acne marks, and other imperfections that affect our appearance. That’s where a combination of laser treatments and skin boosters is very helpful. While injections improve the skin from within, laser brightens up external imperfections, such as dark spots and skin discoloration.
| Combination | Primary Goal | Benefits | Ideal For |
|---|---|---|---|
| Skin Boosters + Dermal Fillers | Volume restoration + hydration | Addresses both structure and skin quality simultaneously | Patients with volume loss and dull skin |
| Skin Boosters + Botulinum Toxins | Dynamic wrinkle prevention + skin quality | Smooth skin with improved texture and hydration | Patients with expression lines and dehydrated skin |
| Skin Boosters + Laser Treatments | Internal + external rejuvenation | Addresses pigmentation, texture, and hydration | Patients with dark spots, scarring, and dull complexion |
Both Profhilo and NCTF 135 HA are effective and popular skin boosters that are widely used in the cosmetic beauty sphere. Both treatments improve skin quality but do not add volume or reshape facial features. They provide long-lasting effects and improve skin from within, which is why the results are striking for people with various cosmetic needs: dryness, dullness, discoloration, and other conditions.
“The decision between NCTF and Profhilo isn’t about which is better—it’s about which is better for this specific patient at this specific time. That’s the art of aesthetic medicine.” — Dr. Isabella Romano, Clinical Director
In order to decide which product is better for one’s needs, a consultation in the doctor’s office is required. It’s important to examine the skin, define the main issues, and tailor the plan that addresses all the problems. The quality of the product is also vital, which is why we recommend picking a reliable supplier to buy your goods, such as FillerCloud!
Fillers restore volume and smooth wrinkles, while skin boosters improve skin quality, texture, and hydration without reshaping facial features.
Patients with dry skin needing deep hydration, those seeking improved skin quality, or anyone wanting significant results without time-consuming procedures.
NCTF 135 HA contains 50+ active ingredients including vitamins and amino acids, while Profhilo focuses on ultra-high concentration ultra-pure hyaluronic acid.
NCTF 135 HA requires three sessions spaced 15 days apart, while Profhilo often needs only one or two treatments.
Despite different formulations, both deeply hydrate skin and support collagen synthesis for even-toned complexion and natural glow.
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